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Prednisone & Weight Gain (The Studies) Many studies have been conducted to evaluate the side effect profile of prednisone and similar corticosteroid medicationsand see if any weight gains are observed by a certain body mass index (BMI). Some of these studies are summarized below:
A 2004 Cochrane review conducted by the United Kingdom’s Royal College of Obstetricians and Gynecologists showed a high risk of weight gain associated with short doses of prednisone. This increased weight gain was seen in women taking 10mg every 2-3 times per day (in excess of the recommended 10-15 mg given to normal healthy postmenopausal women), prednisone, results from anabolic steroids. The highest weight gain occurred with the shortest (5mg) dose, and lowest was with the longest (10mg), best quick steroid cycle.
A 2003 meta-analysis of 25 studies showed that prednisone had a moderate to high risk of weight gain, and that weight loss was associated with a 5% to 10% increase in BMD.
A 2001 meta analysis of 15 randomized controlled trials found that in women taking prednisone the risk of gaining weight was higher than in non-users, and the amount of weight regain was higher as well, cost of steroids per month. No additional weight gain was seen with weight loss.
A 2009 meta-analysis by the American Journal of Clinical Nutrition found a moderate to high risk of weight gain associated with both short- and long-term use of prednisone. A study of 15,823 women found that more than 20% of the women gained 5 percent to 10 percent of their body weight while on the medication, and the most common increase in BMD was 2%.
A 2003 meta-analysis conducted by the Centers for Disease Control and Prevention (CDC) on the health effects of the synthetic estradiol analogs dihydrogestradiol and 19-nor-19-dihydro-beta-D-glucuronide found that these medications are associated with a increased risk of osteoporosis and bone loss, but did not suggest if weight gain or weight loss could be observed with these drugs.
A 1994 study conducted by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) in collaboration with the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS, also NIH), found no differences in weight gain or weight loss between women taking prednisone and those not on the medication, prednisone.
Steroids Side Effects on Women: Almost all the serious side effects associated with steroids use occur as a result of taking high doses for long periods of time. In some cases, steroids cause damage to your liver, bone, heart, kidneys, lungs, nervous system, blood vessels, hair follicles, hair follicle development, heart, adrenal glands, bones, and thyroid glands — and even to you. A few of these side effects are minor, but can lead to serious problems over time due to the cumulative effects. Read on for the full list of side effects of steroids.
Hormone Hormone Use
A steroid can affect all cells in the body — including your blood cells and brain cells. The hormone progesterone has a negative effect on estrogen levels and this affects the immune system. Progesterone may increase your risk of ovarian failure, an ovarian cyst, breast growth, or premenopausal symptoms (such as breast tenderness and breast enlargement). If your testosterone level drops, you may experience low libido, decreased erections, and ejaculation problems. Progesterone also affects the prostate gland and is involved in sexual dysfunction — especially in men.
DHEA DHEA can increase your risk of breast cancer and prostate cancer. It can also cause premature balding of the hair on the head, but this may also lead to baldness in the back or around the groin. The best way to decrease this side effect is by taking DHEA replacement medicine. DHEA is used in women in the treatment of conditions that cause hair and follicular changes.
A Steroid Side Effect: Acne
A common side effect of using steroids is acne. Some acne medications (including oral and topical creams) are used to reduce pimples and other skin ailments. If you use creams or salicylic acids to treat acne, you may also need to take a hormone medication called prednisone (Adapalene). This medication is intended to reduce inflammation caused by severe acne. However, with oral steroids, it is possible they may cause irritation and allergic reactions in some people. In adults, it is also possible the creams can cause blood clots. Also, because there are no known safe oral doses of this medication, it should only be used under medical supervision by a doctor and should not be taken by anyone without treatment.
Other side effects may also occur as a result of taking high doses of steroids. In some cases, women may get acne-like pimples or breakouts on the face, neck and jaw. These may be more severe when taking more than low levels of
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